From: LARRY KLAES (ljk4_at_msn.com)
Date: Wed Feb 05 2003 - 09:46:35 PST
----- Original Message -----
From: cunews_at_cornell.edu
Sent: Thursday, January 30, 2003 5:15 PM
To: CUNEWS-CAMPUS-L_at_cornell.edu
Subject: Cornell News: Ludwig Lecture--decoding the human genome
Next step in decoding human genome to be described by Ludwig
Institute geneticist at Cornell on Feb. 12
FOR RELEASE: Jan. 30, 2003
Contact: Blaine P. Friedlander Jr.
Office: 607-255-3290
E-mail: bpf2_at_cornell.edu
ITHACA, N.Y. -- Andrew Simpson, a senior geneticist with the Ludwig
Institute for Cancer Research in São Paulo, Brazil, will
discuss the challenges that remain in decoding the human genome in a
lecture at Cornell University on Wednesday, Feb. 12, at 4 p.m. in
Room G-10 of the Biotechnology Building.
His lecture, titled "Transcriptomics: The Link Between Sequencing the
Human Genome and Human Biology," is free and open to the public. It
is the third in a series of lectures sponsored by the Cornell/Ludwig
Institute for Cancer Research Partnership.
Simpson, who also is director of the Ludwig Institute's James R. Kerr
Program, led the Brazilian effort to sequence the bacterium Xylella
fastidiosa, the first genome sequencing to be completed outside of
the United States, Europe or Japan. The organism causes severe damage
to citrus trees and the citrus industry.
In his talk Simpson will note that although sequencing of the human
genome is almost complete, a second massive sequencing effort must be
undertaken to permit gene identification. That effort will be
searching for genetic annotations, or "transcripts."
Simpson will describe how a large group of scientists in Brazil,
coordinated by the Ludwig Institute, has contributed about 1 million
sequences from transcripts present in tumors and normal tissues to
public databases.
"We are now embarking on the precise quantification of gene
expression using novel sequencing methods that are capable of
generating several million short tags from individual transcripts
within cells," says Simpson.
The genetic sequencing is capable of tagging even the rarest of
messages that have previously eluded detection. Says Simpson: "We
have now moved in the space of two years from gene discovery within
the human genome to precise quantification of gene expression and
transcript variability using the same basic technique of human
transcript sequencing."
-30-
The web version of this release may be found at
http://www.news.cornell.edu/releases/Jan03/LudwigLecture.bpf.html
Cornell University News Service
Surge 3
Cornell University
Ithaca, NY 14853
607-255-4206
cunews_at_cornell.edu
http://www.news.cornell.edu
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